This module is designed to discuss relevant herbal Materia Medica with therapeutic activity upon the upper and lower gastrointestinal tract, gut microbiome, and gut-brain axis. After completing this module, registrants should be able to differentiate between the major herbal actions and constituents with clinical effects upon the digestive system, understand the pharmacology and primary medicinal indications for a selection of herbs related to the digestive system, and understand how to make ideal herbal choices, dosing, and formulations for common digestive complaints.