Medicinal Herbs and ADHD


Scientific Name: Corydalis ambigua


  • Isoquinoline Alkaloids (Protopine & Protoberberine type; corydaline, bulbocapnine, dl-Tetrahydropalmatine, (dl-THP), protopine, leonticine, ambinine, tetrahydrocoptisine, corybulbine, tetrahydrocolumbamine and tetrahydroberberine (THB)).

Medicinal actions:

  • Analgesic
  • Antispasmodic
  • Anti-viral
  • Nervine Relaxant/Sedative

Mechanism of Action & Pharmacology:

  • Isoquinoline Alkaloids (Protopine & Protoberberine type) have shown to prevent platelet aggregation and also have inhibitory effects on Epstein Barr virus early antigen activation, which may be of value as anti-tumor promoters.
  • Tetrahydroberberine (THB) isolated alkaloid extract prevents platelet aggregation both in-vitro and in-vivo.
  • Bulbocapnine is believed to work with the dopaminergic neuronal transmitter system (potential inhibitory effect).
  • dl-Tetrahydropalmatine (dl-THP) has been shown to possess analgesic activity and also exert sedative-tranquilizing and hypnotic actions. Has also been shown to significantly ameliorate protracted abstinence withdrawal syndrome (PAWS) and the abstinence rate among heroin users.


  • Tincture
  • Decoction
  • Dried rhizome
  • Capsule
  • Best used alongside other nervine relaxants/sedatives

Safety & Toxicity Concerns:

  • In high doses may cause trembling, shaking, twitching, or tics.
  • Avoid in pregnancy & lactation due to unknown effects.


  • May have additive effects with anticoagulant medication.

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