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Scientific Name: Apium graveolens

Constituents:

  • Volatile oil (limonene, selenine & phthalide compounds including phtalidglycosides)
  • Flavonoids (apigenin, apiin, luteolin, chrysoeriol & quercitin)
  • Furanocoumarins
  • Fatty acids (linoleic, myristic, oleic, palmitic, stearic, and petroselinic)
  • Alkaloids
  • Vitamins C, beta-carotene & Minerals (sodium, calcium, iron, potassium)

Medicinal actions:

  • Anti-inflammatory
  • Antimicrobial
  • Anti-rheumatic
  • Bitter
  • Carminative & Antispasmodic
  • Diuretic
  • Emmenagogue (Uterine stimulant)
  • Galactagogue
  • Hypotensive
  • Nervine relaxant

Mechanism of Action & Pharmacology:

  • Volatile oils can cause irritation of the kidneys, which may contribute to diuretic effects.
  • Volatile oils & alkaloids are calming and appear to have depressant, tranquilizing effects on the CNS.
  • Phthalide compounds are antispasmodic, sedative, diuretic & hypotensive.
  • Flavonoids are diuretic, anti-inflammatory, anti-rheumatic & anti-platelet.

Pharmacy:

  • Tincture
  • Dried seed
  • Decoction
  • Fresh seed juice

Safety & Toxicity Concerns:

  • Monitor in hypertension or fluid retention due to sodium content.
  • Furanocoumarins in combination with UV light may cause photodermatitis.
  • Use caution in acute kidney conditions due to the irritating effect of the volatile oils.
  • Avoid in pregnancy due to volatile oils with possible abortifacient effects.
  • Potential for allergy exists.

Interactions:

  • Theoretically reduce serum levels of thyroxine.

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