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Scientific Name: Scutellaria laterifolia

Constituents:

  • Flavonoids & Phenylethanoid glycosides (acteoside, baicalein, baicalin, apigenin, scutellarin, scutellarien & luteolin)
  • Iridoid glycosides (catalpol)
  • Volatile oil (limonene, terpineol, & humulene)
  • Tannins
  • Minerals

Medicinal actions:

  • Antioxidant
  • Antispasmodic
  • Bitter
  • Nervine Tonic & Relaxant (Neuroprotective)
  • Hypotensive

Mechanism of Action & Pharmacology:

  • Flavonoids & diterpenes have been shown to possess wide pharmacological actions, such as antitumor, anti-angiogenesis, hepatoprotective, antioxidant, anti-convulsant, anti-bacterial and anti-viral activities.
  • Flavonoids, including apigenin, scutellarin & luteolin are antispasmodic, anti-inflammatory, and have significant antioxidant effects that will neutralize free radicals, having protective effects against oxidative stress.
  • Scutellarin specifically has calming bitter effects and has demonstrated an ability to inhibit sucrase and maltase and alpha-glucosidase activity, lending potential anti-diabetic effects.
  • Volatile oils limonene, terpineol & humulene are antispasmodic and anti-inflammatory.
  • Flavonoids baicalin and its aglycone baicalein may play a role in anxiolytic & anti-convulsant activity, as they are known to bind to the benzodiazepine site of GABA receptors.

Pharmacy:

  • Infusion
  • Tincture
  • Capsules

Safety & Toxicity Concerns:

  • None known or expected.

Interactions:

  • Theoretical additive effects with CNS depressant medications.

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