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Scientific Name: Verbascum thapsus

Constituents:

  • Phenylethanoid & lignan glycosides (verbascoside)
  • Mucilage & polysaccharides
  • Flavonoids (acubin)
  • Saponins
  • Iridoid glycosides
  • Volatile oil (flowers)
  • Tannins
  • Resins (flowers)
  • Bitter principle

Medicinal actions:

  • Analgesic
  • Anti-inflammatory
  • Anticatarrhal
  • Antimicrobial
  • Demulcent
  • Expectorant (Respiratory Amphoteric)
  • Nervine Relaxant
  • Vulnerary (Emollient)

Mechanism of Action & Pharmacology:

  • Mucilage is anti-inflammatory & primarily responsible for soothing action upon mucous membranes.
  • Saponins may be responsible for the expectorant actions as they draw fluid from the tissues, thereby creating a thinner mucous that is easier to expectorate
  • Flavonoids (e.g. acubin & luteolin) are anti-inflammatory, helping reduce copious mucous production and have showed promising antiproliferative activities, with an effect on inducing apoptosis of lung cancer cells.
  • Iridoid compounds (e.g. verbathasin A) have potential antiangiogenic & antiproliferative activities.
  • Phenylethanoid glycoside (verbascoside) has anti-inflammatory properties, reducing the production of superoxide radicals and activity of iNOS.
  • Volatile oils are antimicrobial, anti-inflammatory & antispasmodic.

Pharmacy:

  • Infusion
  • Tincture
  • Topical: Poultice & infused oils

Safety & Toxicity Concerns:

  • None known.

Interactions:

  • None reported.

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