Scientific Name: Leonurus cardiaca
- Alkaloids (leonurine, betonicine & stachydrine)
- Flavonoids (apigenin, kaempferol, quercitin)
- Glycosides (Bufadienolide & Lavandulifolioside)
- Iridoids & Terpenoids (ursolic acid)
- Volatile oil
- Vitamins A & C
- Cardiac Tonic
- Nervine Tonic & Relaxant
- Uterine tonic & Emmenagogue
Mechanism of Action & Pharmacology:
- Alkaloids & glycosides appear responsible for antispasmodic, hypotensive & vasodilatory effects, which also serves to increase circulation to the reproductive organs and potentially increase uterine contractions. Stachydrine is oxytocic & sedating. Leonurine is uterotonic, sedative, hypotensive, and cardioactive.
- Nervine relaxant and cardiotonic effects attributed to bufadienolide glycosides.
- Ursolic acid is anti-viral, anti-tumor, cytotoxic and inhibits Epstein-Barr.
Safety & Toxicity Concerns:
- Avoid in Pregnancy, lactation and menorrhagia.
- Theoretically may interact with various cardiovascular medications.