Scientific Name: Solidago spp.
Constituents:
- Triterpenoid Saponins
- Flavonoids (rutin & quercitin)
- Phenolic glycosides (leiocarposide & virgaureoside)
- Phenolic acids (caffeic & chlorogenic acids)
- Tannins
- Volatile oil
- Polysaccharides
- Salicylates
Medicinal actions:
- Analgesic
- Anti-microbial
- Anti-inflammatory
- Anti-lithic
- Astringent
- Anti-catarrhal
- Diuretic
- Hepatic
- Immunomodulator
Mechanism of Action & Pharmacology:
- Saponins are antimicrobial, immuno-modulating and have anti-tumor effects.
- Flavonoids are anti-inflammatory, antioxidant, and diuretic.
- Volatile oils are antimicrobial & anti-fungal.
- Cytotoxic effects seem to be related to the presence of triterpenoids, which inhibit the lyase activity of DNA polymerase.
Pharmacy:
- Infusion
- Tincture
- Capsules
- Topical as poultice or compress
Safety & Toxicity Concerns:
- Avoid in known salicylate or Asteraceae allergy, renal and cardiac insufficiency (especially with edema), and in children due to theoretical potential for Reyes Syndrome.
Interactions:
- None known.